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Consistent with this, no neurodegenerative phenotypes are observed in youthful animals in the absence of pathogenic protein expression, suggesting that the metabolite may act most strongly on threshold state animals

Kakkar, S

The IDH3 catalyzed reaction is, therefore, considered the rate-limiting reaction of the cycle

Bile acids signal via TGR5 to activate intestinal stem cells and epithelial regeneration

As a result, the usual acute ulcer repair is unsuccessful

Extremophiles 4(2):9198 Madern D, Ebel C, Mevarech M, Richard SB, Pfister C, Zaccai G (2000) Insights into the molecular relationships between malate and lactate dehydrogenases: structural and biochemical properties of monomeric and dimeric intermediates of a mutant of tetrameric l-[LDH-like] malate dehydrogenase from the halophilic archaeon Haloarcula marismortui
