glutathione cancer hoax Application of depletion in therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy Human cancer-associated fibroblasts enhance glutathione
Description
G.ZareiA.SimpsonJ

Candidate pathways Enzyme-independent oxidation Because GSH oxidation is strongly dependent on deprotonation to the thiolate form (GS), electron transfer is pH-dependent
Systemic inflammatory response syndrome (SIRS): where did it come from and is it still relevant today

CC mainly includes eplasma membrane, membrane raft and cytosol, etc.,

DJ-1 loss by glutaredoxin but not glutathione depletion triggers Daxx translocation and cell death

Furthermore, Lehwald et al
