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The enzyme activity was assayed using the prepared membrane fractions (0.3 mg total protein determined by Bradford assay for each reaction) in the presence of 0.5 mM NADPH and 0.5 mM testosterone in 0.1 M sodium citrate pH 5.0 buffer

10.1073/pnas.72.3.844

But that same triple mechanism means the body needs time to adjust

The use of the term 'toxin' in this context is meaningless

2B, C), confirming that cystine restriction elevates oxidative and ferroptosis stress

The sensitivity of R 4 parameters ( k p4 ) with respect to model OCR output is in good accordance with the AIC/BIC analysis, confirming the need for the R 4 reaction, which is present in both the triad and the comproportionation models, but not in the reduced model