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Have a Gastrointestinal Disorder Individuals with gastrointestinal conditions such as Crohns disease or celiac disease may have difficulty absorbing adequate amounts of vitamin B12

Beyond antioxidant defense, it boosts white blood cell activity to strengthen immune function, helps build collagen in skin, joints, bones, and blood vessels, and speeds tissue repair and wound healing

Both direct antioxidant actions and SIRT1-mediated deacetylation accomplish this

GSH exerts antioxidant activity, so anything which hampers this can have significant consequences

For example, oxidative stress is one of the conditions that induces stress granules (SGs) formation

doi: 10.3389/fimmu.2024.1422940 Received 24 April 2024 Accepted 25 June 2024 Published 09 July 2024 Volume 15 - 2024 Edited by Lucia Mundo, University of Limerick, Ireland Reviewed by Mark Daniel Hicar, University at Buffalo, United States Egidia Miftode, Grigore T