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Methadone dose increased 5 mg/day from an initial 25 mg to a maintenance dose of 60 mg/day

Personal stories may help identify promising areas for research, but they are not a substitute for controlled clinical studies

Fiorucci S, Distrutti E

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A scientific study in murine breast cancer model reported the suppressive effect of EGCG on tumor growth seemed to be closely correlated with the reduced infiltration of TAMs with the downregulation of monocyte chemokines, including macrophage-colony stimulating factor (CSF) -1 and C-C chemokine ligand (CCL) 2 ( Besides macrophage recruitment and infiltration, the phenotype of TAMs in TME is also controlled by EGCG