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155,156 While corticosteroids have shown limited efficacy and potential adverse effects in clinical trials, NSAIDs, particularly those with selective cyclooxygenase-2 inhibition, have demonstrated some protective effects in experimental models

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Once inside host tissue, many putative virulence genes are upregulated in vivo (18, 19)

In this phase, the liver attaches a glutathione molecule to a toxin, making it water-soluble so the body can easily flush it out

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