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The ADA and GPX4 proteins were upregulated in Cis_R T24 cells, whereas GADD45B and TNFAIP8 showed increased expression in Cis_R KU19-19 MIBC cells (Supplementary Fig

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Furthermore, we could identify a SASP gene expression profile (senescence-associated secretory phenotype) 39,40 after TBI (Supplementary Fig

However, excessively high ROS levels can cause severe damage to nucleotides, proteins, cell membranes, and organelles, ultimately leading to cell death

[DOI] [PubMed] [Google Scholar] 130.Tsai T.Y., Kuo C.Y., Huang Y.C

Cellular quality control mechanisms influencing MSC stemness Cellular quality control, including the unfolded protein response and the heat shock proteins, reduces production of defective proteins by refolding, degrading, or delivering to distinct quality control compartments