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Given the medicinal and food functions of PS, it has been influential in preventing diseases and performing healthcare functions

391,396,402,412,413 Hydroxylation of testosterone by the R47L/F87V/L188Q variant generates three primary products, specifically 2-, 15-, and 16-testosterone, whereas the wild-type is incapable of catalyzing this reaction

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doi: 10.3389/fphys.2025.1609555 Received 14 April 2025 Accepted 02 September 2025 Published 18 September 2025 Corrected 28 October 2025 Volume 16 - 2025 Edited by Samad Rahimnejad, University of Murcia, Spain Reviewed by Palash Kumar Pal, University of Calcutta, India Updates Copyright 2025 Kovacik, Helczman, Tomka, Jambor, Kovacikova and Arvay
