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Because of heterogeneity and the lack of high-evidence randomized controlled trials, we were not able to perform an etiology-based meta-analysis on the use of NAC in ALF
2022;375: eabm9609
Click chemistry: diverse chemical function from a few good reactions
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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain
L-serine synthesis via the phosphorylated pathway in humans
