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Conversely, hyperglycemia contributes to the genesis of advanced glycation end products (AGEs), oxidative stress, and inflammation, thereby exacerbating cardiac dysfunction and provoking structural remodeling [612]
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Molecular mechanism of PPARalpha action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
The context of pathway activation matters enormously
fmr1 mutant PyrN at middle exhibited a moderate reduction in dendrite arbor size, whereas fmr1 mutant PyrN at right exhibited severely impaired dendrite growth
H.KerkhofM.et al (2011)
