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An ATP-depleting futile 5-oxoproline cycle related to the glutathione synthetic pathway was recently proposed to explain many of the biochemical features of nephropathic cystinosis (38,39)

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ER-residential Nogo-B accelerates NAFLD-associated HCC mediated by metabolic reprogramming of oxLDL lipophagy

Whales rely on these habitats for their survival

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Specifically, NAC is an acetylated form of the amino acid L-cysteine, which is considered the rate-limiting amino acid for endogenous glutathione synthesis