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Some individuals might use up their B12 reserves quicker than others, requiring more frequent injections

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Sinha RA, Khare P, Rai A, Maurya SK, Pathak A, Mohan V et al (2009) Anti-apoptotic role of omega-3-fatty acids in developing brain: perinatal hypothyroid rat cerebellum as apoptotic model

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Cells of this mutant lack activity of cytoplasmic superoxide dismutase, an enzyme which scavenges superoxide anion radical, and thus are more vulnerable to the harmful effects of reactive oxygen species (ROS), generated both in optimal conditions for yeast growth (mainly as a by-product of oxygen metabolism) and in the presence of pro-oxidants 32

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