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GPX4-negativity, hazard ratio 4.5345, P = 0.0009) independently predicted shorter OS

[DOI] [PubMed] [Google Scholar] 99.Khalid N., Kobayashi I., Neves M.A., Uemura K., Nakajima M

For vitamin B12, this relatively modest daily requirement reflects the body's efficient recycling mechanisms and the vitamin's storage capacity in the liver, which can maintain reserves for several years (typically 2-5 mg)

Sartori SB, Whittle N, Hetzenauer A, Singewald N: Magnesium deficiency induces anxiety and HPA axis dysregulation: Modulation by therapeutic drug treatment

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10.1038/s43587-024-00793-y [DOI] [PMC free article] [PubMed] [Google Scholar] Boccardi V (2025) From telomeres and senescence to integrated longevity medicine: redefining the path to extended healthspan