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This impairment may manifest as fatigue, immune dysfunction, and an increased vulnerability to toxic overload from environmental sources, alcohol, and processed foods

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Orexin A (human, rat, mouse) binds and activates two types of G protein-coupled receptors, the orexin-1 receptor (OX1R) and the orexin-2 receptor (OX2R)

Inherited disorders of vitamin B 12 absorption Rare cases of inborn errors of vitamin B 12 metabolism have been reported in the literature (reviewed in 6)

Chinese Medical Journal , 134 , 21752185

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