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Reactions which may occur because of this solution, added drugs or the technique of reconstitution or administration include febrile response, local tenderness, abscess, tissue necrosis or infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection and extravasation

Many patients notice they fall asleep more easily and wake up feeling more refreshed

Digestive issues such as Crohn's or celiac disease can lead to impaired absorption of nutrients in the gut which may result in the need for B12 supplementation

It is investigated in experimental models for its interaction with growth factor signaling, angiogenesis-related mechanisms, and cytoprotective processes

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