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In contrast, astrocytes exhibit lower expression of pyruvate dehydrogenase (Laughton et al., 2007), which limits oxidative phosphorylation (Itoh et al., 2003) and reduces pyruvate utilization efficiency in the TCA cycle (Rahman et al., 2020)

10.3727/096504016x14685034103590 132 XuA.WangH.HooR
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Innear Ear Pharmacokinetics of JNK Inhibitor SP-600125 FIG

In the contemporary era, research into these bioactive natural products originating from medicinal plants, fungi, and microorganisms is also based on ancient ethnopharmacological (including entheogenic) human practices [367, 590]
But right now, the drug is still being tested
