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Your insurance company may not offer coverage for this medication if you intend to use it for weight loss

While the results from studies using native OXM in rodents and humans were promising, the short half-life in vivo and the large amount of peptide required to produce an effect made it a poor choice as a treatment in humans

For weight management in people without diabetes, NICE recommends considering specific GLP-1 agonists (semaglutide 2.4mg or liraglutide 3mg) only in specialist weight management services, for individuals with a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Black African, or African-Caribbean backgrounds) who have weight-related comorbidities

10.2337/dc20-2877

Regular monitoring by a healthcare professional is crucial to detect and manage these possibilities

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