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In SURMOUNT-1 (NEJM 2022, 2,539 adults with obesity), the 15 mg arm averaged 22.5% body weight loss at 72 weeks, the 10 mg arm 21.4%, and the 5 mg arm 16.0%

2,3 One of the potential differential diagnoses to consider in these patients is cobalamin or vitamin B 12 (B 12 ) deficiency

Many patients get terrific results combining the two

therefore, the use of these agents should be discouraged (Smit et al., 2021)

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However, if the condition is linked to rickets, osteomalacia, or malnutrition, a more specific ICD-10 code should be used