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Since GSTO1 overexpression has been implicated in drug resistance, particularly to platinum compounds 7,18,19 , we tested the effects of GSTO1 inhibitors in combination with cisplatin in HCT116 cells
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It is linked to obesity and cardiometabolic diseases
Collectively, these analyses demonstrate that both mouse demyelination models recapitulate key features of DAOs in MS lesions, including increased TNF and interferon signaling pathways
