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When neurons are damaged, astrocytes optimize their metabolic functions, producing lactate, glutamate, and ketone bodies to provide necessary energy and maintain extracellular homeostasis (Herrera Moro Chao et al., 2022)

Introduction Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality globally, accounting for 32% of all deaths (1)

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Detachment of cytochrome c from cardiolipin might also be triggered by increased cytosolic calcium, which weakens the electrostatic interaction between cytochrome c and cardiolipin and further generates ROS via MPT

10.1073/pnas.2411280122 74

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