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Clinical Update 8/22/2024 Leg Cramps and Carnitine Does taking L-carnitine or acetyl-L-carnitine reduce leg cramps

Schizophrenia Research has also highlighted the role of acyl-carnitines, derivatives of L-carnitine involved in cellular energy production, in schizophrenia

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Studies in Crat knockout mice demonstrated that CrAT deficiency leads to abnormal fuel selection, which results in a perturbation of glucose homeostasis and suggest that deficits in CrAT activity might contribute to diet-induced metabolic inflexibility by exacerbating the Randle glucose-fatty acid cycle 66