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DPOAE threshold was defined as the interpolated value of f2 intensity required to generate a 0 dB SPL DPOAE

These alternative routes, however, are insufficient to maintain as high an NADPH/NADP ratio as the oxPPP, leading to downstream consequences including altered folate redox status due to impairment of dihydrofolate reductase activity by NADP 57

2026;13(7):e16794

Gradually, yes
