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Description
Recently, the results of a landmark randomized controlled trial showed treatment with tirzepatide (15 mg subcutaneous/week), a dual GLP-1R/GIP receptor (GIPR) agonist, caused an 18% placebo-subtracted weight loss (21% total weight loss) at 72 weeks in people with obesity (6)
Limited research is available, and improper handling or consumption could lead to adverse effects

[PubMed: 2104624] 366

The best way to maintain long-term results is to maintain a healthy weight and lifestyle

doi: 10.1007/s12020-013-0093-x 222 DuhamelCIlieMDSalleHNassouriASGaillardSDelucheEet al

Setting Realistic Expectations Understanding the typical semaglutide timeline helps prevent discouragement during the early weeks when dose adjustments may cause temporary side effects and weight loss is just beginning