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The considerable increase in CAT activity observed in leaves can protect chloroplasts, which under stress conditions present sustained electron flows and are the main producers and targets of ROS action [34]

Methylated B vitamins - particularly B12, B6, B9 (folate) - are all necessary for one-carbon metabolism

Function and mechanisms of truncated BDNF receptor TrkB

Keywords: TCA cycle, epigenetics, inflammation, ROS, acetyl-CoA, l-2HG, l-2-hydroxyglutarate INTRODUCTION Adaptive immunity comprises individual cells that change state, proliferate, migrate, and exert effector functions

Our findings suggest that modulating the iron/FoxO1/hepatokine axis could represent an approach to addressing metabolic dysfunction in MASLD, potentially offering greater specificity than global FoxO1 inhibition