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The Kuzminski trial involved 33 patients (18 in the oral arm and 15 in the intramuscular arm), while the Bolaman trial involved 60 (26 in the oral arm and 15 in the intramuscular arm)

Vitamin B12 deficiency and use of proton pump inhibitors: systematic review

NHS therapeutic doses for deficiency are far higher than standard dietary reference values

This is often referred to as a washout period

its impairment leads to accumulation of methylmalonic acid, which is associated with neurological damage

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