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10.1016/j.aninu.2019.06.004 Anim
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10.3390/molecules26061547 127 PinheiroR
Recent progress in the discovery and development of small-molecule modulators of CFTR
Rapamycin mitigates NLRP3 inflammasome activation by inhibiting the mTOR complex 1 (mTORC1), which directly reduces A1 astrocyte formation and enhances autophagy-mediated removal of damaged cellular components, thereby attenuating neuroinflammation (304306)
Young age
We identified the conserved interaction between WW domains of cellular ubiquitin ligases of the Nedd4 family and a short peptide motif (PPxY) present in several structural and non-structural viral proteins as a potential drug target
