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Neferine inhibits LPS-ATP-induced endothelial cell pyroptosis via regulation of ROS/NLRP3/Caspase-1 signaling pathway

References Godlewska BR, Williams S, Emir UE, Chen C, Sharpley AL, Goncalves AJ, et al

doi: 10.1158/2159-8290.CD-16-0932

Italy Russia Asia-Pacific: China Japan South Korea India Australia China Taiwan Indonesia Thailand Malaysia Latin America: Mexico Brazil Argentina Korea Colombia Middle East & Africa: Turkey Saudi Arabia UAE Korea In North America, the United States dominates the market, boasting a size of over $600 billion, primarily driven by technology and healthcare sectors

NAC crosses the blood-brain barrier, increases brain GSH levels, and acts as a glutamine modulator (11)
PLoS ONE 7:e34015 Magi S, Arcangeli S, Castaldo P, Nasti AA, Berrino L, Piegari E, Bernardini R, Amoroso S, Lariccia V (2013) Glutamate-induced ATP synthesis: relationship between plasma membrane Na +/Ca2 + exchanger and excitatory amino acid transporters in brain and heart cell models