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(1) The studies on the anti- chemoradiotherapy-related cardiotoxicity of TCM are limited to OS, inflammation, apoptosis, autophagy, ERS, and myocardial energy metabolism, but other important mechanisms such as Top2 have not been addressed, and many investigations into TCM have only studied one of these mechanisms, which is not conducive to our comprehensive understanding of the mechanisms of anti-cardiotoxicity of TCM

Benfotiamine protects against hypothalamic dysfunction in a STZ-induced model of neurodegeneration in rats

It is a type of B vitamin, and its shortage results in lower red blood cell count or abnormal enlargement of these cells

Luna B, Marek S, Larsen B, Tervo-Clemmens B, Chahal R

Adems se observ una correlacin entre los niveles de mercurio (Hg) y aluminio (Al) en pelo y dichos sistemas antioxidantes endgenos

Mechanistically, the incubation of hemin with thiols (GSH, NAC, cysteine, mercaptoethanol, and thioglycolic acid) provokes major spectrophotometric changes in hemin despite the presence of low-affinity binders in serum [222]