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The 6J substrain has a deficiency of the mitochondrial enzyme nicotinamide nucleotide transhydrogenase (NNT), which transfers electron from NADH to NADP + thereby supporting the antioxidant glutathione peroxidase in mitochondria

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[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Cash A, Kaufman DL

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