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In transfusion medicine, these discoveries contribute to advancements in storage methodologies, including metabolic rejuvenation and focused modulation of membrane pathways to mitigate storage lesions and enhance post-transfusion effectiveness (80)

Science 340 , 701706 (2013)

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In this process, ROS production by the RBOHs, RBOHD and RBOHF, is triggered in the cells that are directly subjected to stress, resulting in a state of activated ROS production