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In either case, because of the decreased activity of this enzyme and insufficient production of NADPH under stress, the cell's ability to recycle GSSG to GSH is impaired, and drug-induced oxidative stress leads to excessive damage and lysis of RBCs (hemolysis) and hemolytic anemia
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In case of an Adverse Analytical Finding (AAF) in-competition, the athlete may apply for a retroactive TUE as provided for in the applicable rules
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