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This is due to the strong homeostasis of vitamin E, which keeps the blood concentration constant on account of vitamin E in the tissues

Khan MA & Tania M (2012) Nutritional and medicinal importance of Pleurotus mushrooms: an overview

A concentration of 50 mol/L artesunate selectively induces cell death in head and neck cancer cells without affecting normal cells by activating an iron-dependent, ROS-accumulating ferroptosis pathway [139]

Elsevier, 187212

1, 25-dihydroxyvitamin D3 regulates the synthesis of gamma-glutamyl transpeptidase and glutathione levels in rat primary astrocytes

When supplementation stops, glutathione levels may gradually return to baseline depending on diet, lifestyle, and overall health.