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Similarly, SURMOUNT 3 showed a mean BW reduction of 18.4% with tirzepatide titrated to the maximum tolerated dose (15 mg for 86% participants) after a 72-week follow-up 35

If a timepoint for blood collection of 1 h post ingestion is selected, the FITC-Dextran assay will represent small intestinal permeability, whilst longer timepoints (46 h) will represent whole gut permeability

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This was not the case for Frank Macfarlane Burnet (figure 12), appointed the director of the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne in 1944

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