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doi: 10.1186/2045-9912-2-15

The peroxidase and oxidase-like activity of NiCo 2 O 4 mesoporous spheres: mechanistic understanding and colorimetric biosensing

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The high neutrophil to lymphocyte ratio in critically ill patients, the intense neutrophil infiltration in pulmonary capillaries and into pulmonary alveoli, and the increased levels of circulating neutrophil extracellular traps (NETs) clearly show neutrophil involvement/activation favoring intense ROS production and oxidative damage caused by lipid peroxidation, and protein and DNA oxidation (Komaravelli and Casola, 2014

Figure 8 6.3.2 Antioxidant drugs When many more free radicals [like reactive oxygen/nitrogen species (ROS and NOS)] are produced in human bodies, causing the amount to exceed the scavenging capability of antioxidant enzymes and other antioxidants (like glutathione and vitamins), the free radicals that are not scavenged will oxidate nucleic acids, proteins, and lipids, leading to serious damage of cells and tissues