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Moderate glutathione synthetase deficiency leads to hemolytic anemia and metabolic acidosis, whereas patients with a more severe deficiency also develop 5-oxoprolinuria, recurrent bacterial infections, and progressive dysfunction of the central nervous system, including mental retardation and motor functional disturbances
N Engl J Med 389:205214 Choi H, Ryu S, Keir HR et al (2023) Inflammatory molecular endotypes in bronchiectasis: a European multicenter cohort study
The injected medication relaxes the blood vessels, allowing for better circulation
it induces the production of free radicals in the short term but increases antioxidant production over the long term
10.1089/ars.2011.4475 281 RaoulC.BuhlerE.SadeghiC.JacquierA.AebischerP.PettmannB.et al
[PubMed ID: 3015905]
