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Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxyge-nase dependent- and AIF-mediated cell death

American Journal of Chinese Medicine

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Reeves Eyre JEJ, Zhu J, Kumar A, Wang W (2024) Diurnal variability of the upper ocean simulated by a climate model

Notably, acetylcarnitine can act as an acetyl donor [37], supporting the acetylation process of cells through the shuttle mechanism of acetylcarnitine in the absence of conventional acetyl-CoA synthetase enzymes such as ATP-citrate lyase (ACLY) and acyl-CoA synthetase short chain 2 (ACSS2) [38]

These findings suggested that folic acid supplementation could be a novel therapeutic strategy to combat ferroptosis in age-related neuronal damage