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[DOI] [PMC free article] [PubMed] [Google Scholar] [95]

[4] In animals, Semax rapidly elevates the levels and expression of brain-derived neurotrophic factor (BDNF) and its signaling receptor tropomyosin receptor kinase B (TrkB) in the hippocampus, [15] and rapidly activates serotonergic and dopaminergic brain systems

However, it was not an obligatory intermediate in the formation of the mature BDNF (11)
It aligns with cortisol peaks and prepares the body for daytime demands, offering steady, clean energy
