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Pharmacotherapy 31 , 12571264

In addition, TMAO was suggested to activate NFB, likely through a G-protein coupled receptor G signaling pathway in endothelial cells and vascular smooth muscle cells, leading to enhanced expression of proinflammatory cytokines and leukocyte adhesion to endothelial cells in vitro (Seldin et al., 2016)

Apoyo mitocondrial: Finalmente, protege las mitocondrias del estrs oxidativo, lo que contribuye a mejorar su eficiencia

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However, it should be noted as mentioned previously, in conditions where it does not increase glucose oxidation, carnitine supplementation worsens both injury and recovery of contractile function after transient ischemia in the perfused rat heart [122]