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Moreover, iron accumulation in activated microglia contributes to iron deposition within the CNS (51,52)

Ben-Jonathan, N., LaPensee, C

W., To K

J Agri Tech

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SAT1 activation can induce ferroptosis, while P53 can induce SAT1 transcriptional expression to promote lipid peroxidation and ROS-induced ferroptosis, and silencing SAT1 diminishes ROS-induced cellular ferroptosis in wild-type P53 cells [123, 124]
