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Within these studies, increased NET formation was also specifically associated with certain complications of COVID-19 infections, including vascular occlusion and pneumocyte damage, allowing NETs to be labelled as multi-purposed in the immune response against SARS-CoV-2 and other viruses [26, 28,29,30,31]

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Moreover, the sulfenic acid in PTP1B undergoes intramolecular attack by the adjacent amide nitrogen atom which results in the formation of an isothiazolidinone species also referred to as a sulfenyl amide (Fig

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10.1016/j.immuni.2013.05.015 157 YangP.QianF

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