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therefore, three strains of Lactobacillus , each shown alone to have a protective effect against the development of EAE when administered before disease onset, were shown to inhibit established disease when administered as a therapeutic mixture

10.1073/pnas.0402959101 Proc

Early histological studies examining skin wounds, colon anastomoses, and sponge implantation models evaluated tissue organization parameters such as reticulin fibers, collagen architecture, and blood vessel formation in healing tissue environments [8]

Oxid Med Cell Longev 2013: 940603, 2013

We would like to point out that it is always a possibility for inhibitors identified through design or screening to hit multiple target proteins, not just the intended one

IFN--induced or poly (I:C)-induced anoikis results in the impairment of secretory gland function and high titers of autoimmune antibodies in serum (152)