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The light chain of the HAT transporters is variable and dictates specific amino acid cargos 31

The expanding scope of antimicrobial peptide structures and their modes of action

14 certain adverse effects are classified as idiosyncratic, and typically occur early after initiating therapy and often require drug discontinuation: flu-like syndrome (fever, nausea, skin rash, body ache, and headache), gastrointestinal intolerance, and acute pancreatitis

Sasaki K, Jabbour E, Kantarjian HM, Cortes JE, Garcia-Manero G, Borthakur G , Pierce SR, Pemmaraju N, OBrien S, Ravandi F

Unlike some other peptides, it has a selective action on increasing growth hormone secretion, minimizing unwanted side effects

Tirzepatide with niacinamide follows the same principle