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10.1038/ajg.2011.103 Am J Gastroenterol

doi: 10.12691/jfnr-3-9-6 6 StefaniMRigacciS
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Acute kava usage caused reversible anesthesia of the mouth and skin, euphoria, sedation, muscle weakness, ataxia and, eventually, intoxication
Innovations like liposomal encapsulation or prodrug forms (e.g., S-acetyl glutathioe) aim to enhance delivery.Taken together, oral glutathiona capsules stand out as a versatile multi-target antioxidant nutritional supplement that addresses systemic oxidative stress spanning nervous, hepatic, respiratory, cutaneous and immune systems

Chiefly, the reaction between different organic ligands and Hg produces R-Hg + and R-Hg-R compounds