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[DOI] [PMC free article] [PubMed] [Google Scholar] 39.Asrani S., Bacharach J., Holland E., McKee H., Sheng H., Lewis R.A., Kopczynski C.C., Heah T

Serotonin is a precursor to melatonin and has its own role in modulating sleep-wake cycles

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For example, a study of MTHFR polymorphism genotypes in colorectal cancer patients reported that the frequency of methylated Bcl-2 promoter was significantly higher in individuals with CC genotype than that of those with CT and TT genotypes, and a significant difference of C and T alleles distribution were observed between patients with methylated and unmethylated Bcl-2 promoter 35

Now, you need to help the powder dissolve

DSIP is thought to increase production of GABA (20)a neurotransmitter that slows brain activity, promotes relaxation, and increases time spent in deep sleep
