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"Some people are deficient and feel a lot better when given a shot, but just to pep you up, there's no study that says it's helpful." B12 is created by bacteria, including those living in the digestive tract

Data are expressed as means SE

162 Another trial in 32 patients with human immunodeficiency virus (HIV) compared the effect of a daily multi-strain probiotic supplement to placebo or no supplement

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