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Increases in TMAO levels during CVD/T2D progression (beyond the observed wide natural interindividual variability in TMAO levels) could be the result of disease-related dysbiosis

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doi: 10.1021/jm060153i

D-carnitine supplementation has been found to induce liver inflammation, oxidative stress, and apoptosis in animal studies (13)

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44 identified a positive correlation between PD-L1 and HIF-1 in intracranial gliomas, further indicating that HIF-1 facilitates PD-L1 expression, consistent with our findings