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2 Pathogenesis of pulmonary fibrosis Tissue repair following injury is an inherent biological mechanism that restores tissue integrity through the organized replacement of damaged or deceased cells (Figure 1: the initial sustained injury phase, the inflammatory cell migration phase, the fibroblast migration/proliferation/activation phase and finally, the excessive deposition of ECM and fibrosis phase

The main challenge with oral glutathione supplements is their poor bioavailability

Blood tests including hemoglobin and hematocrit should be done to determine the adequacy of therapy

Rats prenatally exposed to VPA and treated with NAC from PND 21 to PND 35 (Group VPA/NAC)

Tight control of the glutamate content outside of cells is essential because of its pivotal function in neuronal signaling

Green-synthesized MSNs using the plant polyphenols or chitosan further enhance additional selectivity against less cytotoxic parasites in mammalian cells [279]