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Description
Resibufogenin (RB) inhibited colorectal cancer cell growth and tumorigenesis through triggering ferroptosis and ROS production mediated by GPX4 inactivation

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Mechanisms include melanocortin-receptor signaling and direct intracellular NF-kappaB inhibition

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One of the noninvasive strategies to treat these disorders is to control melanogenesis by inhibiting tyrosinase gene expression

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