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In humans, mutations in the HNF1B gene are associated with pancreatic hypoplasia, defective kidney development and genital malformations

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Factors influencing gel-strengthening at the mucoadhesive-mucus interface

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Possible explanations include atypical dietary intake, altered gut microbial liberation of coumarin from plant polyphenols, or reduced hepatic detoxification

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This is particularly important, because the regulation of PI-PLCs or PI-PLC-dependent signaling pathways can be important for understanding both the normal cellular physiology and the pathogenesis of important diseases, possibly leading to the development of innovative therapeutic strategies or the comprehension of new molecular processes

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