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No serious adverse events documented in widespread use though systematic safety data absent

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.RT

Associated symptoms typically include, diarrhoea, rectal bleeding, urgency to defecate and incontinence

Contains 100 mcg B 12 , 100 mg niacinamide, 100 mg B 1 , 10 mg B 6 , 10 mg d-panthenol and 5 mg B 2 per ml

Lucchinetti and colleagues categorized patterns of pathology into distinct lesion types, all of which contain T-cell, plasma cell, and macrophage infiltrates [65, 67]

Typical oral protocols use 0.5 mg to 1 mg daily, often split into two doses taken morning and evening